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The risk of developing these severe side effects is very small, but it is important that patients and healthcare professionals are aware and alert to the associated symptoms. An estimated 1.6 million UK adults used GLP-1s such as semaglutide (Wegovy, Ozempic) and tirzepatide (Mounjaro) to lose weight between early 2024 and early 2025, with an additional 3.3 million interested in using weight loss drugs during 2026

It does not stimulate insulin secretion, so it carries minimal hypoglycaemia risk on its own

Reta's GLP-1 component suppresses appetite, which can mask early hypoglycemia warning signs